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Accueil > Biotechnology and cell signalling (Jean-Luc Galzi)
(UMR 7242)
> Genome integrity and tumor biology (Scientific coordination : Valérie Schreiber) > Nuclear signalling and cancererology > Publications > Publications of the team

Publications of the team

Updated : 09/26/2016

2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 |

 

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- 2016

Martinez-Zapien D., Ruiz F.X., Poirson J., Mitschler A., Ramirez J., Forster A., Cousido-Siah A., Masson M., Vande Pol S., Podjarny A., Travé G. & Zanier K.
Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53.
Nature 2016, 529, 541-545 - DOI

Travé G. & Zanier K.
HPV-mediated inactivation of tumor suppressor p53.
Cell Cycle 2016, 15, 2231-2 - DOI

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- 2015

Vincentelli R.* Luck.*, Poirson J., Polanowska J., Abdat J., Blémont M., Turchetto, J., Iv F., Ricquier K., Straub M.L., Forster A., Cassonnet P., Borg J.P., Jacob Y., Masson M., Nominé Y., Reboul J., Wolff N., Charbonnier S. & Travé G.
High-throughput determination of domain-ligand affinities by automated holdup assay allows quantification of linear motif specificities.
Nature Methods, 12, 787-793 - DOI * equal contribution

Stutz C., Reinz E., Honegger A., Bulkescher J., Schweizer J, Zanier K., Travé G., Lohrey C., Hoppe-Seyler K. & Hoppe-Seyler F.
Intracellular analysis of the interaction between the Human Papillomavirus type 16 E6 oncoprotein and inhibitory peptides.
Plos One 10, e0132339 - DOI

Ramirez J., Poirson J., Foltz C., Chebaro Y., Meyer A., Bonetta A., Jacob Y., Masson M., Deryckère F & Travé G.
Targeting the two oncogenic functional sites of HPV E6 oncoprotein with a high-affinity bivalent ligand.
Angew. Chem. Int Ed Engl. 54, 7958-7962 - DOI

Bonetta A.C., Mailly L., Robinet E., Travé G., Masson M., Deryckere F.
Artificial microRNAs against the viral E6 protein provoke apoptosis in HPV positive cancer cells.
_ Biochem. Biophys. Res. Commun. 465, 658-664 - DOI

Tsakogiannis D, Gortsilas P, Kyriakopoulou Z, Ruether IG, Dimitriou TG, Orfanoudakis G, Markoulatos P.
Site of disruption within E1 and E2 genes of HPV16 and association with cervical dysplasia.
J Med Virol. 87,1973-80 - DOI

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- 2014

Asencio-Hernández J1, Ruhlmann C, McEwen A, Eberling P, Nominé Y, Céraline J, Starck JP, Delsuc MA.
Reversible amyloid fiber formation in the N terminus of androgen receptor.
Chembiochem. 2014, 15, 2370-3 - DOI

Postupalenko V, Sibler AP, Desplancq D, Nominé Y, Spehner D, Schultz P, Weiss E, Zuber G.
Intracellular delivery of functionally active proteins using self-assembling pyridylthiourea-polyethylenimine.
J Control Release. 2014, 27, 549-58 - DOI

Pulka-Ziach K, Pavet V, Chekkat N, Estieu-Gionnet K, Rohac R, Lechner MC, Smulski CR, Zeder-Lutz G, Altschuh D, Gronemeyer H, Fournel S, Odaert B, Guichard G.
Thioether Analogues of Disulfide-Bridged Cyclic Peptides Targeting Death Receptor 5: Conformational Analysis, Dimerisation and Consequences for Receptor Activation.
Chembiochem. 2014, - DOI

Zanier K, Stutz C, Kintscher S, Reinz E, Sehr P, Bulkescher J, Hoppe-Seyler K, Travé G, Hoppe-Seyler F.
The E6AP Binding Pocket of the HPV16 E6 Oncoprotein Provides a Docking Site for a Small Inhibitory Peptide Unrelated to E6AP, Indicating Druggability of E6.
PLoS One. 2014, 9, e112514 - DOI

Belyaeva TA, Nicol C, Cesur O, Travé G, Blair GE, Stonehouse NJ.
An RNA Aptamer Targets the PDZ-Binding Motif of the HPV16 E6 Oncoprotein.
Cancers (Basel). 2014, 6, 1553-69 - DOI

Grindheim AK, Hollås H, Ramirez J, Saraste J, Travé G, Vedeler A.
IEffect of serine phosphorylation and Ser25 phospho-mimicking mutations on nuclear localisation and ligand interactions of annexin A2.
J Mol Biol. 2014 , 426, 2486-99 - DOI

Martinez-Zapien D1, Delsuc MA1, Travé G2, Lutzing R1, Rochette-Egly C1, Kieffer B
Production and characterization of a retinoic acid receptor RARγ construction encompassing the DNA binding domain and the disordered N-terminal proline rich domain.
Protein Expr Purif. 2014, 95, 113-20 - DOI

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- 2013

Baltzinger M, Sharma KK, Mély Y, Altschuh D
Dissecting the oligonucleotide binding properties of a disordered chaperone protein using surface plasmon resonance.
Nucleic Acids Res. 2013, 41, 10414-25 - DOI

Choulier L, Nominé Y, Zeder-Lutz G, Charbonnier S, Didier B, Jung ML, Altschuh D.
Chemical library screening using a SPR-based inhibition in solution assay: simulations and experimental validation.
Anal Chem. 2013, 85, 8787-8795 - DOI

Zanier K., Charbonnier S., Ould M’hamed ould Sidi A., McEwen AG., Giovanna Ferrario M., Poussin-Courmontagne P., Cura V., Brimer N., Ould Babah K., Ansari T., Muller I., Stote RH., Cavarelli J., Vande Pol S., Travé G.
Structural basis for hijacking of cellular LxxLL motifs by papillomavirus E6 oncoproteins.
Science. 2013 Feb 8, 339(6120), 694-8 - DOI

Zeder-Lutz G, Renau-Ferrer S, Aguié-Béghin V, Rakotoarivonina H, Chabbert B, Altschuh D, Rémond C.
Novel surface-based methodologies for investigating GH11 xylanase-lignin derivative interactions.
Analyst. 2013, 138 - DOI

Zidane F, Zeder-Lutz G, Altschuh D, Girardet JM, Miclo L, Corbier C, Cakir-Kiefer C.
Surface plasmon resonance analysis of the binding mechanism of pharmacological and peptidic inhibitors to human somatic angiotensin I-converting enzyme.
Biochemistry. 2013 52, 8722-8731 - DOI

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- 2012

Altschuh D, Björkelund H, Strandgård J, Choulier L, Malmqvist M, Andersson K.
Deciphering complex protein interaction kinetics using Interaction Map.
Biochem Biophys Res Commun. 2012, 428, 74-79 - DOI

Brenner AK., Kieffer B., Travé G., Frøystein NA., Raae AJ.
Thermal stability of chicken brain α-spectrin repeat 17: a spectroscopic study.
Journal of Biomolecular NMR. 2012, 53(2), 71-83 - DOI

Dinkel H., Michael S., Weatheritt RJ., Davey NE., Van Roey K., Altenberg B., Toedt G., Uyar B., Seiler M., Budd A., Jödicke L., Dammert MA., Schroeter C., Hammer M., Schmidt T., Jehl P., McGuigan C., Dymecka M., Chica C., Luck K., Via A., Chatr-Aryamontri A., Haslam N., Grebnev G., Edwards RJ., Steinmetz MO., Meiselbach H., Diella F., Gibson TJ.
ELM—the database of eukaryotic linear motifs.
Nucleic Acids Res. 2012, 40(Database issue), D242-51 - DOI

El-Andaloussi N., Bonifati S., Kaufmann JK., Mailly L., Daeffler L., Deryckère F., Nettelbeck DM., Rommelaere J., Marchini A.
Generation of an adenovirus-parvovirus chimera with enhanced oncolytic potential.
J Virol. 2012, 86(19), 10418-31 - DOI

Freisz S., Mezher J., Hafirassou L., Wolff P., Nominé Y., Romier C., Dumas P., Ennifar E.
Sequence and structure requirements for specific recognition of HIV-1 TAR and DIS RNA by the HIV-1 Vif protein.
RNA Biol. 2012, 9(7), 966-977- DOI

Luck K., Charbonnier S., Travé G.
The emerging contribution of sequence context to the specificity of protein interactions mediated by PDZ domains.
FEBS Letters 2012, 586(14), 2648–2661 - DOI

Neveu G., Cassonnet P., Vidalain PO., Rolloy C., Mendoza J., Jones L., Tangy F., Muller M., Demeret C., Tafforeau L., Lotteau V., Rabourdin-Combe C., Travé G., Dricot A., Hill DE., Vidal M., Favre M., Jacob Y.
Comparative analysis of virus–host interactomes with a mammalian high-throughput protein complementation assay based on Gaussia princeps luciferase.
Methods. 2012, sous presse - DOI

Weatheritt R., Luck K., Petsalaki E., Davey N., Gibson T.
The identification of short linear motif-mediated interfaces within the human interactome.
Bioinformatics. 2012, 28(7), 976-982 - DOI

Zanier K., Ould M’hamed ould Sidi A., Boulade-Ladame C., Rybin V., Chappelle A., Atkinson A., Kieffer B. and Travé G.
Solution structure analysis of HPV 16 E6 oncoprotein reveals a self-association mechanism required for E6-mediated degradation of p53.
Structure. 2012, 20(4), 604-17 - DOI

Zeder-Lutz G, Choulier L, Besse M, Cousido-Siah A, Ruiz Figueras FX, Didier B, Jung ML, Podjarny A, Altschuh D.
Validation of surface plasmon resonance screening of a diverse chemical library for the discovery of protein tyrosine phosphatase 1b binders.
Anal Biochem. 2012, 421, 417-427 - DOI

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- 2011

Bernard X., Robinson P., Nominé Y., Masson M., Charbonnier S., Ramirez-Ramos JR., Deryckere F., Travé G., Orfanoudakis G.
Proteasomal Degradation of p53 by Human Papillomavirus E6 Oncoprotein Relies on the Structural Integrity of p53 Core Domain.
PLoS One. 2011, 6(10), e25981 - DOI

Boumlic A., Vassilaki N., Dalagiorgou G., Kochlios E., Kakkanas A., Georgopoulou U., Markoulatos P., Orfanoudakis G., Mavromara P.
Internal translation initiation stimulates expression of the ARF/core+1 open reading frame of HCV genotype 1b.
Virus Res. 2011, 155(1), 213-20 - DOI

Burnouf D.Y., Ennifar E., Guedich S., Puffer B., Hoffmann G., Bec G., Disdier F., Baltzinger M., Dumas P.
kinITC: a new method for obtaining joint thermodynamic and kinetic data by Isothermal Titration Calorimetry.
J. Am. Chem. Soc. 2011, 1, 559-565- DOI

Charbonnier S., Nominé Y., Ramirez J., Luck K., Chapelle A., Stote RH., Travé G., Kieffer B., Atkinson RA.
The structural and dynamic response of MAGI-1 PDZ1 with non-canonical domain boundaries to binding of human papillomavirus (HPV) E6.

J Mol Biol. 2011, 406(5), 745-63 - DOI

Dalagiorgou G., Vassilaki N., Foka P., Boumlic A., Kakkanas A., Kochlios E., Khalili S., Aslanoglou E., Veletza S., Orfanoudakis G., Vassilopoulos D., Hadziyannis S., Koskinas J., Mavromara P.
High Levels of HCV core+1 Antibodies in HCV Patients with Hepatocellular Carcinoma.
J Gen Virol. 2011, 92(Pt 6), 1343-51 - DOI

Davey NE., Travé G., Gibson TJ.
How viruses hijack cell regulation.

Trends Biochem Sci. 2011, 36(3), 159-69 - DOI

Davranche A., Aviolat H., Zeder-Lutz G., Busso D., Altschuh D., Trottier Y., Klein F.A.
Huntingtin affinity for partners is not changed by polyglutamine length: aggregation itself triggers aberrant interactions.
Hum. Mol. Genet. 2011, 20, 2795-806. - DOI

Fournane S., Charbonnier S., Chapelle A., Kieffer B., Orfanoudakis G., Travé G., Masson M., Nominé Y.
Surface plasmon resonance analysis of the binding of high-risk mucosal HPV E6 oncoproteins to the PDZ1 domain of the tight junction protein MAGI-1.
J Mol Recognit. 2011, 24(4), 511-23 - DOI

Fugier C., Klein AF., Hammer C., Vassilopoulos S., Ivarsson Y., Toussaint A., Tosch V., Vignaud A., Ferry A., Messaddeq N., Kokunai Y., Tsuburaya R., de la Grange P., Dembele D., Francois V., Precigout G., Boulade-Ladame C., Hummel MC., de Munain AL., Sergeant N., Laquerrière A., Thibault C., Deryckere F., Auboeuf D., Garcia L., Zimmermann P., Udd B., Schoser B., Takahashi MP., Nishino I., Bassez G., Laporte J., Furling D., Charlet-Berguerand N.
Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy.
Nature Medicine. 2011, 17(6), 720-5 - DOI

Hammani K., Gobert A., Hleibieh K., Choulier L., Small I., Giegé P.
An Arabidopsis dual-localized pentatricopeptide repeat protein interacts with nuclear proteins involved in gene expression regulation.
Plant Cell. 2011, 23, 730-40. - DOI

Löfås S, Choulier L., Zeder-Lutz G;, Baltzinger M., Altschuh D.
Surface Plasmon Resonance
in: «Biophysical approaches determining ligand binding to biomolecular targets» 2011 (Podjarny A., Dejaegere A., Kieffer B., eds), RCS Publishing, London, UK,

Luck K., Travé G.
Phage display can select over-hydrophobic sequences that may impair prediction of natural domain-peptide interactions.
Bioinformatics. 2011, 27(7), 899-902 - DOI

Luck K., Fournane S., Kieffer B., Masson M., Nominé Y., Travé G.
Putting into Practice Domain-Linear Motif Interaction Predictions for Exploration of Protein Networks.
PLoS One. 2011, 6(11), e25376 - DOI

Ould M’hamed Ould Sidi A., Ould Babah K., Brimer N., Nominé Y., Romier C., Kieffer B., Vande Pol S., Travé G., Zanier K.
Strategies for bacterial expression of protein-peptide complexes: Application to solubilization of papillomavirus E6.
Protein Expr Purif. 2011, 80(1), 8-16 - DOI

Trave G.
PDZ-Peptide Complexes: As Exciting as Ever.
Structure. 2011, 19(10), 1350-1 - DOI

Zeder-Lutz G., Choulier L., Besse M., Cousido-Siah A., Figueras F.X., Didier B., Jung M.L., Podjarny A., Altschuh D.
Validation of surface plasmon resonance screening of a diverse chemical library for the discovery of protein tyrosine phosphatase 1b binders.
Anal. Biochem. 2011 ( in press)- DOI

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- 2010

Boumlic A., Nominé Y., Charbonnier S., Dalagiorgou G., Vassilaki N., Kieffer B., Travé G., Mavromara P., Orfanoudakis G.
Prevalence of intrinsic disorder in the hepatitis C virus ARFP/Core+1/S protein.

FEBS J. 2010 277, 774-89 - DOI

Choulier L., Shvadchak V.V., Naidoo A., Klymchenko A.S., Mély Y., Altschuh D.
A peptide-based fluorescent ratiometric sensor for quantitative detection of proteins.
Anal. Biochem. 2010 401, 188-95 - DOI

Fu L., Van Doorslaer K., Chen Z., Ristriani T., Masson M., Travé G., Burk R.D.
Degradation of p53 by human Alphapapillomavirus E6 proteins shows a stronger correlation with phylogeny than oncogenicity.
PLoS One. 2010 5, pii: e12816 - DOI

Gould C.M., Diella F., Via A., Puntervoll P., Gemünd C., Chabanis-Davidson S., Michael S., Sayadi A., Bryne J.C., Chica C., Seiler M., Davey N.E., Haslam N., Weatheritt R.J., Budd A., Hughes T., Pas J., Rychlewski L., Travé G., Aasland R., Helmer-Citterich M., Linding R., Gibson T.J.
ELM: the status of the 2010 eukaryotic linear motif resource.
Nucleic Acids Res. 2010 38 (Database issue) D167-80 - DOI

Timmerman P., Geifman Shochat S., Desmet J., Barderas R., Casal J.I., Meloen R.H., Altschuh D.
Binding of CDR-derived peptides is mechanistically different from that of high-affinity parental antibodies.
J. Molec. Recognit. 2010 23, 559-68 - DOI

Zanier K., Ruhlmann C., Melin F., Masson M., Ould M’hamed Ould Sidi A., Bernard X., Fischer B., Brino L., Ristriani T., Rybin V., Baltzinger M., Vande Pol S., Hellwig P., Schultz P., Travé G.
E6 proteins from diverse papillomaviruses self-associate both in vitro and in vivo.
J. Mol. Biol. 2010 396, 90-104 - DOI

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- 2009

Diella, F., Chabanis, S., Luck, K., Chica, C., Ramu, C., Nerlov, C., and Gibson, TJ.
KEPE - a motif frequently superimposed on sumoylation sites in metazoan chromatin proteins and transcription factors.
Bioinformatics 2009 25, 1-5 - DOI

Radi M., Maga G., Alongi M., Angeli L., Samuele A., Zanoli S., Bellucci L., Tafi A., Casaluce G., Giorgi G., Armand-Ugon M., Gonzalez E., Esté J.A., Baltzinger M., Bec G., Dumas P., Ennifar E., Botta M.
Discovery of chiral cyclopropyl dihydro-alkylthio-benzyl-oxopyrimidine (S-DABO) derivatives as potent HIV-1 reverse transcriptase inhibitors with high activity against clinically relevant mutants.
J. Med. Chem. 2009 52, 840-51 - DOI

Rich R.L., Papalia G.A., Flynn P.J., Furneisen J., Quinn J., Klein J.S., Katsamba P.S., Waddell M.B., Scott M., Thompson J., Berlier J., Corry S., Baltzinger M., Zeder-Lutz G., et al.
A global benchmark study using affinity-based biosensors.
Anal. Biochem. 2009. 386, 194-216 - DOI

Ristriani T., Fournane S., Orfanoudakis G., Travé G., Masson M.
A single-codon mutation converts HPV16 E6 oncoprotein into a potential tumor suppressor, which induces p53-dependent senescence of HPV-positive HeLa cervical cancer cells.
Oncogene 2009 28, 762-772 - DOI

Timmerman P., Barderas R., Desmet J., Altschuh D., Shochat S., Hollestelle M.J., Höppener J.W., Monasterio A., Casal J.I., Meloen R.H.
A combinatorial approach for the design of complementarity-determining region-derived peptidomimetics with in vitro anti-tumoral activity.
J Biol Chem. 2009 284, 34126-34 - DOI

Van Doorslaer K., Ould M’hamed Ould Sidi A., Zanier K., Rybin V., Deryckere F., Rector A., Burk R.D., Lienau E.K., van Ranst M., Travé G.
Identification of unusual E6 and E7 proteins within avian papillomaviruses: cell localization, biophysical characterization and phylogenetic analysis.
J. Virol., 2009 83, 8759-70 - DOI

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- 2008

Barderas R., Shochat S., Timmerman P., Hollestelle M.J., Martínez-Torrecuadrada J.L., Höppener J.W.M., Altschuh D., Meloen R., Casal J.I
Designing antibodies for the inhibition of gastrin activity in tumoral cell lines.
Int. J. Cancer 2008 22, 2351-9 - DOI

Charbonnier S., Stier G., Orfanoudakis G., Kieffer B., Atkinson R.A., Travé G.
Defining the minimal interacting regions of the tight junction protein MAGI-1 and HPV16 E6 oncoprotein for solution structure studies.
Prot. Expr. Purif. 2008 60, 64-73 - DOI

Diella F., Haslam N., Chica C., Budd A., Michael S., Brown N., Travé G., Gibson T.J.
Understanding eukaryotic linear motifs and their role in cell signaling and regulation.
Front Biosci. 2008 1, 6580-603 - DOI

Duszczyk, M.M., Zanier, K., Sattler, M.
A NMR strategy to unambiguously distinguish nucleic acid hairpin and duplex conformations applied to a Xist RNA A-repeat.
Nucleic Acids Res 36, 7068-77 - DOI

Enander K., Choulier L., Olsson L., Yushchenko D.A., Kanmert D., Klymchenko A.S., Demchenko A.P., Mély Y., Altschuh D.
A peptide-based, ratiometric biosensor construct for direct fluorescence de- tection of a protein analyte.
Bioconjug. Chem. 2008 19, 1864-70 - DOI

Greenwald J., Zeder-Lutz G., Hagege A., Célia H., Pattus F.
The metal dependence of pyoverdine interactions with its outer membrane receptor FpvA.
J. Bacteriol. 2008 190, 6548-58 - DOI

Greschik H., Althage M., Flaig R., Sato Y., Peluso-Iltis C., Chavant V., Choulier L., Cronet P., Rochel N., Schüle R., Strömstedt P.E., Moras D.
Communication between the ERR alpha homodimer interface and the PGC- 1alpha binding surface vie the helix 8-9 loop.
J. Biol. Chem. 2008 283, 20220-30 - DOI

Lagrange M., Boulade-Ladame C., Orfanoudakis G., Deryckere F.
Modification of adenovirus type 5 tropism for a preferential transduction of human papillomavirus-positive cancer cells.
Arch. Virol. 2008 153, 1921-25 - DOI

Mailly L., Boulade-Ladame C., Orfanoudakis G., Deryckere F.
A novel adenovirus vector for easy cloning in the E3 region downstream of the CMV promoter
Virol. J. 2008 5, 73 - DOI

Michael S., Travé G., Ramu C., Chica C., Gibson TJ.
Discovery of candidate KEN-box motifs using cell cycle keyword enrichment combined with native disorder prediction and motif conservation.
Bioinformatics 2008 15, 453-7 - DOI

Nominé, Y., Botuyan, MV., Bajzer, Z., Owen, WG., Caride, AJ., Wasielewski, E., Mer, G.
Kinetic analysis of interaction of BRCA1 tandem breast cancer c-terminal domains with phosphorylated peptides reveals two binding conformations.
Biochemistry 47, 9866-79 - DOI

Roldós V., Martín-Santamaría S., Julián M., Martínez A., Choulier L., Altschuh D., de Pascual-Teresa B., Ramos A.
Small molecule negative modulators of adrenomedullin: design, synthesis, and 3D-QSAR study.
Chem. Med. Chem. 2008 3, 1345-55 - DOI

Sibler A.P., Baltzinger M., Choulier L., Desplancq D., Altschuh D.
SPR identification of mild elution conditions for affinity purification of E6 oncoprotein, using a multivariate experimental design.
J. Mol. Recognit. 2008 21, 46-54 - DOI

Sidi, AO., Zanier, K., Travé, G.
Optimising recombinant production of recalcitrant proteins prone to aggregation: the case of papillomavirus E6 oncoproteins.
FEBS J. 2008 275 (S1), 173

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- 2007

Aukrust I., Hollås H., Strand E., Evensen L., Travé G., Flatmark T., Vedeler A.
The mRNA-binding site of annexin A2 resides in helices C-D of its domain IV.
J. Mol. Biol. 2007 368, 1367-78 - DOI

Courtête J., Sibler A.-P., Zeder-Lutz G., Dalkara D., Oulad-Abdelghani M., Zuber G., Weiss E.
Suppression of cervical carcinoma cell growth by intracytoplasmic codelivery of anti-oncoprotein E6 antibody and small interfering RNA.
Mol. Cancer Ther. 2007 6, 1728-35 - DOI

Erdag B., Balcioglu K.B., Kumbasar A., Celikbicak O., Zeder-Lutz G., Altschuh D., Salih B., Baysal K.
Novel short peptides isolated from phage display library inhibit vascular endothelial growth factor activity.
Molec. Biotechnology 2007 35, 51-63- DOI

Klein F.A., Pastore A., Masino L., Zeder-Lutz G., Nierengarten H., Oulad- Abdelghani M., Altschuh D., Mandel J.-L., Trottier Y.
Pathogenic and non-pathogenic polyglutamine tracts have similar structural properties: towards a length-dependent toxicity gradient.
J. Mol. Biol. 2007 371, 235-44- DOI

Lafont V., Schaefer M., Stote R.H., Altschuh D., Dejaegere A.
Protein-protein recognition and interaction hot spots in an antigen-antibody complex: free energy decomposition identifies «efficient amino acids».
Proteins 2007 67, 418-34_ J. Mol. Biol. 2007 371, 235-44- DOI

Lagrange M., Boulade-Ladame C., Mailly L., Weiss E., Orfanoudakis G., Deryckère F.
Intracellular scFvs against the viral E6 oncoprotein provoke apoptosis in human papillomavirus-positive cancer cells.
Biochem. Biophys. Res. Commun. 2007 361, 487-92 - DOI

Zanier K., Nominé Y., Charbonnier S., Ruhlmann C., Schultz P., Schweizer J., Travé G.
Formation of well-defined soluble aggregates upon fusion to MBP is a generic property of E6 proteins from various human papillomavirus species.
Protein Expr. Purif. 2007 51, 59-70 - DOI

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- 2006

Ab, E., A.R. Atkinson, L. Banci, I. Bertini, S. Ciofi-Baffoni, K. Brunner, T. Diercks, V. Dotsch, F. Engelke, G.E. Folkers, C. Griesinger, W. Gronwald, U. Gunther, M. Habeck, R.N. de Jong, H.R. Kalbitzer, B. Kieffer, B.R. Leeflang, S. Loss, C. Luchinat, T. Marquardsen, D. Moskau, K.P. Neidig, M. Nilges, M. Piccioli, R. Pierattelli, W. Rieping, T. Schippmann, H. Schwalbe, G. Travé, J. Trenner, J. Wohnert, M. Zweckstetter, R. Kaptein
NMR in the SPINE Structural Proteomics project.
Acta Crystallogr. D Biol. Crystallogr. 2006 62, 1150-61

Adams, H., G. Zeder-Lutz, I. Schalk, F. Pattus, H. Célia
Interaction of TonB with the outer membrane receptor FpvA of Pseudomonas aeruginosa.
J. Bacteriol. 2006 188, 5752-61

Altschuh D., Oncul S., Demchenko A.P.
Fluorescence sensing of intermolecular interactions and development of di- rect molecular biosensors.
J. Mol. Recognit. 2006 19, 459-77

Andre, N., N. Cherouati, C. Prual, T. Steffan, G. Zeder-Lutz, T. Magnin, F. Pattus, H. Michel, R. Wagner, C. Reinhart
Enhancing functional production of G protein-coupled receptors in Pichia pastoris to levels required for structural studies via a single expression screen.
Protein Sci. 2006 15, 1115-26

Aukrust, I., L. Evensen, H. Hollas, F. Berven, R.A. Atkinson, G. Travé, T. Flatmark, A. Vedeler
Engineering, biophysical characterisation and binding properties of a soluble mutant form of annexin A2 domain IV that adopts a partially folded conformation.
J. Mol. Biol. 2006 363, 469-81

Barderas R, Shochat S, Martínez-Torrecuadrada J, Altschuh D, Meloen R, Ignacio Casal J.
A fast mutagenesis procedure to recover soluble and functional scFvs from synthetic and semisynthetic antibody libraries.
J. Immunol. Meth. 2006 312, 182-189.

Charbonnier, S., M.A. Coutouly, B. Kieffer, G. Travé, R.A. Atkinson
13C, 15N and 1H resonance assignment of the PDZ1 domain of MAGI-1 using QUASI.
J. Biomol. NMR 2006 36 Suppl 1, 33

Charbonnier, S., K. Zanier, M. Masson, G. Travé
Capturing protein-protein complexes at equilibrium: the holdup comparative chromatographic retention assay.
Protein Expr. Purif. 2006 50, 89-101

Dennehy KM, E.F., Zeder-Lutz G, Ding X, Zigan P, Altschuh D, Fred Lühder F, Hünig T.
Monovalency of CD28 maintains the antigen-dependence of T cell co-stimulatory responses.
J. Immunol. 2006 259, 77-86

Lescrinier, E., Nauwelaerts, K., Zanier, K., Poesen, K., Sattler, M., Herdewijn, P.
The naturally occurring N6-threonyl adenine in anticodon loop of Schizosaccharomyces pombe tRNAi causes formation of a unique U-turn motif.
Nucleic Acids Res. 2006 34, 2878-86

Lundstrom, K., R. Wagner, C. Reinhart, A. Desmyter, N. Cherouati, T. Magnin, G. Zeder-Lutz, M. Courtot, C. Prual, N. Andre, G. Hassaine, H. Michel, C. Cambillau, F. Pattus
Structural genomics on membrane proteins: comparison of more than 100 GPCRs in 3 expression systems.
J. Struct. Funct. Genomics 2006 7, 77-91

Nominé, Y., M. Masson, S. Charbonnier, K. Zanier, T. Ristriani, F. Deryckere, A.P. Sibler, D. Desplancq, R.A. Atkinson, E. Weiss, G. Orfanoudakis, B. Kieffer, G. Travé
Structural and functional analysis of E6 oncoprotein: insights in the molecular pathways of human papillomavirus-mediated pathogenesis.
Mol. Cell 2006 21, 665-78

Pimienta, G., Gabel, F., Zanier, K., Conti, E., Sattler, M.
Chemical shift backbone assignments of TAP-N, the 31 kDa cargo-binding region of the protein TAP.
J. Biomol. NMR 2006 36(Suppl), 1:23

Soares, LM., Zanier, K., Mackereth, C., Sattler, M., Valcárcel, J.
Intron removal requires proofreading of U2AF/3’ splice site recognition by DEK.
Science 2006 312, 1961-5

Zeder-Lutz, G., N. Cherouati, C. Reinhart, F. Pattus, R. Wagner
Dot-blot immunodetection as a versatile and high-throughput assay to evaluate recombinant GPCRs produced in the yeast Pichia pastoris.
Protein Expr. Purif. 2006 50, 118-27.

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- 2005

Choulier, L., D. Altschuh, G. Zeder-Lutz, M. Van Regenmortel
Biosensor characterization of structure-function relationships in viral proteins.
Methods in Microbiology 2005 34, 213-238

Dejaegere, A., L. Choulier, V. Lafont, E. De Genst, D. Altschuh
Variations in antigen-antibody association kinetics as a function of pH and salt concentration: a QSAR and molecular modeling study.
Biochemistry 2005 44, 14409-18

Lagrange, M., S. Charbonnier, G. Orfanoudakis, P. Robinson, K. Zanier, M. Masson, Y. Lutz, G. Travé, E. Weiss, F. Deryckere
Binding of human papillomavirus 16 E6 to p53 and E6AP is impaired by monoclonal antibodies directed against the second zinc-binding domain of E6.
J. Gen. Virol. 2005 86, 1001-7

Nominé, Y., S. Charbonnier, L. Miguet, N. Potier, A. Van Dorsselaer, R.A. Atkinson, G. Travé, B. Kieffer
1H and 15N resonance assignment, secondary structure and dynamic behaviour of the C-terminal domain of human papillomavirus oncoprotein E6.
J. Biomol. NMR 2005 31, 129-41

Robinson, P., D. Stuber, F. Deryckere, P. Tedbury, M. Lagrange, G. Orfanoudakis
Identification using phage display of peptides promoting targeting and internalization into HPV-transformed cell lines.
J. Mol. Recognit. 2005 18, 175-82

Sibler, A.P., J. Courtete, C.D. Muller, G. Zeder-Lutz, E. Weiss
Extended half-life upon binding of destabilized intrabodies allows specific detection of antigen in mammalian cells.
FEBS J. 2005 272, 2878-91

Zanier, K., S. Charbonnier, M. Baltzinger, Y. Nominé, D. Altschuh, G. Travé
Kinetic analysis of the interactions of human papillomavirus E6 oncoproteins with the ubiquitin ligase E6AP using surface plasmon resonance.
J. Mol. Biol. 2005 349, 401-12

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- 2004

Botuyan, MV., Nominé, Y., Yu, X., Juranic, N., Macura, S., Chen, J., Mer, G.
Structural basis of BACH1 phosphopeptide recognition by BRCA1 tandem BRCT domains.
Structure 2004 12, 1137-46

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- 2003

Bjorndal, B., G. Travé, I. Hageberg, J.R. Lillehaug, A.J. Raae
Expression and purification of receptor for activated C-kinase 1 (RACK1).
Protein Expr. Purif. 2003 31, 47-55

Masson, M., C. Hindelang, A.P. Sibler, G. Schwalbach, G. Travé, E. Weiss
Preferential nuclear localization of the human papillomavirus type 16 E6 oncoprotein in cervical carcinoma cells.
J. Gen. Virol. 2003 84, 2099-104

Nominé, Y., S. Charbonnier, T. Ristriani, G. Stier, M. Masson, N. Cavusoglu, A. Van Dorsselaer, E. Weiss, B. Kieffer, G. Travé
Domain substructure of HPV E6 oncoprotein: biophysical characterization of the E6 C-terminal DNA-binding domain.
Biochemistry 2003 42, 4909-17

Sibler, A.P., A. Nordhammer, M. Masson, P. Martineau, G. Travé, E. Weiss
Nucleocytoplasmic shuttling of antigen in mammalian cells conferred by a soluble versus insoluble single-chain antibody fragment equipped with import/export signals.
Exp. Cell Res. 2003 286, 276-87

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- 2002

Blusch J. H., Deryckere F., Windheim M., Ruzsics Z., Arnberg N., Adrian T., Burgert, H.G.
The novel early region 3 protein E3/49K is specifically expressed by adenoviruses of subgenus D: implications for epidemic keratoconjunctivitis and adenovirus evolution.
Virology 2002 296, 94-106

Choulier L., Orfanoudakis G., Robinson P., Laune D., Ben Khalifa M., Granier C., Weiss E., Altschuh, D.
Comparative properties of two peptide-antibody interactions as deduced from epitope delineation.
J. Immunol. Methods 2002 259, 77-86

Ristriani, T., Nominé, Y., Laurent, C., Weiss, E.,Travé, G.
Protein mutagenesis with monodispersity-based quality probing: selective inactivation of p53 degradation and DNA-binding properties of HPV E6 oncoprotein.
Protein Expr. Purif. 2002 26, 357-67

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- 2001

Choulier L., Laune D., Orfanoudakis G., Wlad H., Janson J., Granier C., Altschuh, D.
Delineation of a linear epitope by multiple peptide synthesis and phage display.
J Immunol Methods 2001 249, 253-64

Kempf E., Weiss E., Klein P., Glacet A., Spratt S., Bourel D., Orfanoudakis, G.
The rescue by phage display of human Fabs to gp120 HIV-1 glycoprotein using EBV transformed lymphocytes.
Mol. Biotechnol. 2001 17, 97-108

Nominé Y., Ristriani T., Laurent C., Lefevre J.-F., Weiss, E., Travé G.
A strategy for optimizing the monodispersity of fusion proteins: application to purification of recombinant HPV E6 oncoprotein.
Protein Eng. 2001 14, 297-305

Nominé Y., Ristriani T., Laurent C., Lefevre J.-F., Weiss E., Travé, G.
Formation of soluble inclusion bodies by hpv e6 oncoprotein fused to maltose-binding protein.
Protein Expr. Purif. 2001 23, 22-32

Ristriani T., Nominé Y., Masson M., Weiss E., Travé, G.
Specific recognition of four-way DNA junctions by the C-terminal zinc-binding domain of HPV oncoprotein E6.
J. Mol. Biol. 2001 305, 729-39

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