Partenaires

CNRS
Logo Université de Strasbourg
Logo IREBS



Rechercher

Sur ce site

Sur le Web du CNRS


Accueil > Biotechnology and cell signalling (Jean-Luc Galzi)
(UMR 7242)
> Receptors, membrane proteins and therapeutic innovation (Scientific coordination : Isabelle Schalk) > GPCRs, pain and inflammation (Frédéric Simonin) > Publications > Publications of the team RCPG, pain and inflammation

Publications of the team RCPG, pain and inflammation

Updated : 09/27/2016

2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 |

 

- Back to the team home page

 

- 2016

Guillemyn K., Starnowska J., Lagard C., Dyniewicz J., Rojewska E., Mika J., Chung N.N., Utard V., Kosson P., Lipkowski A.W., Chevillard L., Arranz-Gibert P., Teixidó M., Megarbane B., Tourwé D., Simonin F., Przewlocka B., Schiller P.W., Ballet S.
Bifunctional Peptide-Based Opioid Agonist-Nociceptin Antagonist Ligands for Dual Treatment of Acute and Neuropathic Pain.
J. Med. Chem. 2016, 28, 3777-92 - DOI

Logez C., Damian M., Legros C., Dupré C., Guéry M., Mary S., Wagner R., M’Kadmi C., Nosjean O., Fould B., Marie J., Fehrentz J.A., Martinez J., Ferry G., Boutin J.A., Banères J.-L.
Detergent-free Isolation of Functional G Protein-Coupled Receptors into Nanometric Lipid Particles.
Biochemistry 2016 55, 38-48- DOI

Quillet R., Ayachi S., Bihel F., Elhabazi K., Ilien* B., Simonin* F. (* equal authors)
RF-amide neuropeptides and their receptors in Mammals : Pharmacological properties, drug development and main physiological functions.
Pharmacol. Ther. 2016 160, 84-132 - DOI

Roeckel* L.-A., Le Coz* G.-M., Gavériaux-Ruff# C., Simonin# F. (*, # equal authors)
Opioid-induced hyperalgesia: cellular and molecular mechanisms.
Neurosci. 2016, S0306-4522(16)30259-7 - DOI

Westh Hansen R., Wang X., Golab A., Bornert O., Oswald C., Wagner R., Martinez K.L.
Functional Stability of the Human Kappa Opioid Receptor Reconstituted in Nanodiscs Revealed by a Time-Resolved Scintillation Proximity Assay.
PLoS One 2016 11, e0150658- DOI

Buffel I., Meurs A., Portelli J., Raedt R., De Herdt V., Poppe L., De Meulenaere V., Wadman W., Bihel F., Schmitt M., Vonck K., Bourguignon J.-J., Simonin F., Smolders I., Boon P.
The effect of Neuropeptide FF in the amygdala kindling model.
Acta Neurol. Scand. 2016 - DOI

Top of page

 

- 2015

Abboud D., Daubeuf F., Do Q.T., Utard V., Villa P., Haiech J., Bonnet D., Hibert M., Bernard P., Galzi J.L.*, Frossard N.* (* equal authors)
A strategy to discover decoy chemokine ligands with an anti-inflammatory activity,
Sci. Rep. 2015, 7, 14746 - DOI

Bihel F., Humbert J.-P., Schneider S., Bertin I., Wagner P., Schmitt M., Laboureyras E., Petit-Demoulière B., Schneider E., Mollereau C., Simonnet G., Simonin* F., Bourguignon* J.-J. (*equal authors)
Development of a peptidomimetic antagonist of the neuropeptide FF receptors for the prevention of opioid-induced hyperalgesia.
ACS Chem. Neurosci. 2015 6, 438-445 - DOI

Buffel I., Meurs A., Portelli J., Raedt R., De Herdt V., Poppe L., De Meulenaere V., Wadman W., Bihel F., Schmitt M., Vonck K., Bourguignon J.-J., Simonin F., Smolders I., Boon P.
The effect of Neuropeptide FF in the amygdala kindling model.
Acta Neurol. Scand. 2015 - DOI

Buffel I., Meurs A., Portelli J., Raedt R., De Herdt V., Sioncke L., Wadman W., Bihel F., Schmitt M., Vonck K., Bourguignon J.-J., Simonin F., Smolders I., Boon P.
Neuropeptide FF and prolactin releasing peptide decrease cortical excitability through activation of NPFF receptors.
Epilepsia 2015 56, 489-498 - DOI

Galzi J.-L., Ruggiu F., Gizzi P., Didier B.
Quality control of chemical libraries.
Med. Sci. (Paris) 2015 31, 660-666 - DOI

Guilini C., Baehr C., Schaeffer E., Gizzi P., Rufi F., Haiech J., Weiss E., Bonnet D., Galzi J.-L.
New fluorescein precursors for live bacteria detection.
Anal. Chem. 2015 87, 8858-8866 - DOI

Hounsou C., Margathe J.-F., Oueslati N., Belhocine A., Dupuis E., Thomas C., Mann A., Ilien B., Rognan D., Trinquet E., Hibert M., Pin J.-P., Bonnet D., Durroux T.
Time-resolved FRET binding assay to investigate hetero-oligomer binding properties: Proof of concept with dopamine D1/D3 heterodimer.
ACS Chem. Biol. 2015 10, 466-474 - DOI

Lecat S., Belemnaba L., Galzi J.-L., Bucher B.
Neuropeptide Y receptor mediates activation of ERK1/2 via transactivation of the IGF receptor.
Cell Signal. 2015 27, 1297-1304 - DOI

Lecat S., Matthes H.W., Pepperkok R., Simpson J.C., Galzi J.-L.
A Fluorescent Live Imaging Screening Assay Based on Translocation Criteria Identifies Novel Cytoplasmic Proteins Implicated in G Protein-coupled Receptor Signaling Pathways.
Mol. Cell Proteomics 2015 14, 1385-1399 - DOI

Portelli J.*, Meurs A.*, Bihel F., Hammoud H., Schmitt, M. De Kock J., Humbert J.-P. , Bertin I., Utard V., Buffel I., Coppens J., Tourwe D., Maes V., Vanhaecke T., Massie A., Balasubramaniam A., Boon P., Michotte Y., Bourguignon J.-J.*, Simonin* F., Smolders* I. (* equal authors)
Neuropeptide FF receptors as novel targets for limbic seizure attenuation.
Neuropharmacol. 2015 95, 415-423 - DOI

Rouméas L., Humbert J.-P., Schneider S., Doebelin C., Bertin I., Schmitt M., Bourguignon J.-J., Simonin* F., Bihel* F. (*equal authors)
Effects of systematic N-terminus deletions and benzoylations of endogenous RF-amide peptides on NPFF1R, NPFF2R, GPR10, GPR54 and GPR103 Peptides.
Peptides 2015 71, 156-61 - DOI

Schneider S., Ftouni H., Niu S., Schmitt M., Simonin F., Bihel F.
Rapid and scalable synthesis of innovative unnatural α,β or γ-amino acids functionalized with tertiary amines on their side-chains.
Org. Biomol. Chem. 2015 13, 7020-7026 - DOI

Zirafi O., Kim K.E., Ständker L., Mohr K., Sauter D., Heigele A., Kluge S.F., Wiershinska E., Chudziak D., Richter R., Möpps B.,Gierschik P., Vas V., Geiger H., Lamla M, Weil T., Burster T., Zgraja A., Daubeuf F., Frossard N., Hachet-Haas M., Heunisch F., Reichetzeder C., Galzi J.-L., Perez-Castells J., Canales-Mayordomo A., Jiménez-Barbero J.,Giménez-Gallego G., Schneider M., Shorter J., Telenti A., Hocher B., Forssmann W.G., Bonig H., Kirchhoff F., Münch J.
Discovery and characterization of an endogenous CXCR4 antagonist.
Cell Rep. 2015 11, 737-747- DOI

Top of page

 

- 2014

Ayachi S, Simonin F.
Involvement of Mammalian RF-Amide Peptides and Their Receptors in the Modulation of Nociception in Rodents.
Front Endocrinol. 2014 5, 158 - DOI

Elhabazi K, Ayachi S, Ilien B, Simonin F.
Plasma membrane translocation of REDD1 governed by GPCRs contributes to mTORC1 activation.
J Vis Exp. 2014, 89, e51264 - DOI

Logez C, Berger S, Legros C, Banères JL, Cohen W, Delagrange P, Nosjean O, Boutin JA, Ferry G, Simonin F, Wagner R.
Recombinant human melatonin receptor MT1 isolated in mixed detergents shows pharmacology similar to that in mammalian cell membranes.
PLoS One. 2014, 9, e100616 - DOI

Romain B, Hachet-Haas M, Rohr S, Brigand C, Galzi JL, Gaub MP, Pencreach E, Guenot D.
Hypoxia differentially regulated CXCR4 and CXCR7 signaling in colon cancer.
Mol Cancer. 2014 14, 13-58 - DOI

Michel G, Matthes HWD, Hachet-Haas M, El Baghdadi K, de Mey J, Pepperkok R, Simpson JC, Galzi J-L, Lecat S.
Plasma membrane translocation of REDD1 governed by GPCRs contributes to mTORC1 activation.
J. Cell Sci. 2014, 15, 773-787 - DOI

Ruggiu F, Gizzi P, Galzi JL, Hibert M, Haiech J, Baskin I, Horvath D, Marcou G, Varnek A.
Quantitative structure-property relationship modeling: a valuable support in high-throughput screening quality control.
Anal Chem. 2014, 86, 2510-20 - DOI

Top of page

 

- 2013

Bornert O, Møller TC, Boeuf J, Candusso MP, Wagner R, Martinez KL, Simonin F
Identification of a novel protein-protein interaction motif mediating interaction of GPCR-associated sorting proteins with G protein-coupled receptors.
PLoS One. 2013, 8(2):e56336

Daubeuf F, Hachet-Haas M, Gizzi P, Gasparik V, Bonnet D, Utard V, Hibert M, Frossard N, Galzi JL
An antedrug of the CXCL12 neutraligand blocks experimental allergic asthma without systemic effect in mice.
J Biol Chem. 2013, 288(17):11865-76

Daval SB, Kellenberger E, Bonnet D, Utard V, Galzi JL, Ilien B
Exploration of the orthosteric/allosteric interface in human M1 muscarinic receptors by bitopic fluorescent ligands.
Mol. Pharmacol. 2013, 84:71-85

Doebelin C, Wagner P, Bertin I, Simonin F, Schmitt M, Bihel F, Bourguignon J-J
Trisubstitution of pyridine through sequential and regioselective palladium cross-coupling reactions affording analogs of known GPR54 antagonists.
RSC Adv. 2013, 3:10296-10300

Elhabazi K, Humbert J-P, Bertin I, Schmitt M, Bihel F, Bourguignon J-J, Bucher B, Becker JAJ, Sorg T, Meziane H, Petit-Demoulière B, Ilien B, Simonin F
Modulation of nociception and morphine analgesia by endogenous mammalian RF-amide peptides, including PrRP, kisspeptin and 26RFa, via NPFF receptors.
Neuropharmacol. 2013, 75:164-171

Elhabazi K., Ayachi S., Ilien B., Simonin F
Assessment of morphine-induced hyperalgesia and analgesic tolerance in mice using thermal and mechanical nociceptive modalities.
J Vis Exp. 2013 (in press)

Michel G, Matthes HWD, Hachet-Haas M, El Baghdadi K, de Mey J, Pepperkok R, Simpson JC, Galzi J-L, Lecat S
Plasma membrane translocation of REDD1 governed by GPCRs contributes to mTORC1 activation.
J. Cell Sci. 2013 (in press)

Puglia AL, Rezende AG, Jorge SA, Wagner R, Pereira CA, Astray RM
Quantitative RT-PCR for titration of replication-defective recombinant Semliki Forest virus.
J Virol Methods. 2013, 193(2):647-52
Top of page

 

- 2012

Bornert O., Alkhalfioui F., Logez C., Wagner R.
Overexpression of Membrane Proteins using Pichia pastoris.
Curr. Protoc. Protein Sci. 2012, Chapter 29:Unit 29.2 - DOI

Bouchery T, Dénécé G, Attout T, Ehrhardt K, Lhermitte-Vallarino N, Hachet-Haas M, Galzi JL, Brotin E, Bachelerie F, Gavotte L, Moulia C, Bain O, Martin C.
The chemokine CXCL12 is essential for the clearance of the filaria Litomosoides sigmodontis in resistant mice.
PLoS One. 2012;7(4):e34971 - DOI

Daval SB, Valant C, Bonnet D, Kellenberger E, Hibert M, Galzi JL, Ilien B.
Fluorescent derivatives of AC-42 to probe bitopic orthosteric/allosteric binding mechanisms on muscarinic M1 receptors.
J Med Chem. 2012, 55(5), 2125-2143 - DOI

Elhabazi K., Trigo J.-M., Mollereau C., Moulédous L., Zajac J.-M., Bihel F., Schmitt M., Bourguignon J.-J., Meziane H., Petit-demoulière B., Bockel F., Maldonado R., Simonin F.
Involvement of neuropeptide FF receptors in neuroadaptative responses to acute and chronic opiates treatments.
British J. Pharmacol. 2012, 165(2):424-435 - DOI

Galzi J.-L., Haas M., Frossard N., Hibert M.
Why and how to find neutraligands targeting chemokines?
Drug Discovery Today: Technologies 2012, in press

Galzi JL, Ilien B.
G protein-coupled receptors: allosteric regulators of cell metabolism.
Med Sci (Paris) 2012, 28, 852-857 - DOI

Gasparik V., Daubeuf F., Hachet-Haas M., Rohmer F., Gizzi P., Haiech J., Galzi J.-L., Hibert M., Bonnet D., Frossard N.
Prodrugs of a CXCL12 neutraligand active in vivo in a new asthma model.
ACS Medicinal Chemistry Letters 2012, in press

Gealageas R, Schneider S, Humbert JP, Bertin I, Schmitt M, Laboureyras E, Dugave C, Mollereau C, Simonnet G, Bourguignon JJ, Simonin F, Bihel F.
Development of sub-nanomolar dipeptidic ligands of neuropeptide FF receptors.
Bioorg Med Chem Lett. 2012, 22(24):7471-7474 - DOI

Logez C., Alkhalfioui F., Byrne B., Wagner R.
Preparation of Pichia pastoris expression plasmids.
Methods Mol. Biol. 2012, 866:25-40 - DOI

Singh S., Gras A., Fiez-Vandal C., Martinez M., Wagner R., Byrne B.
Screening for High-Yielding Pichia pastoris Clones: The Production of G Protein-Coupled Receptors as a Case Study.
Methods Mol. Biol. 2012, 866:65-73 - DOI

Singh S., Gras A., Fiez-Vandal C., Martinez M., Wagner R., Byrne B.
Large scale production of membrane proteins in Pichia pastoris: the production of GPCRs as a case study.
Methods Mol. Biol. 2012, 866:197-207 - DOI

Top of page

 

- 2011

Alkhalfioui F., Logez C., Bornert O., Wagner R.
Expression systems: Pichia pastoris.
In: Production of Membrane Proteins – Strategies for Expression and Isolation - Editor: Robinson A.S., Wiley-VCH 2011 pp. 75-108 - ISBN: 978-3-527-32729-4

Andersson D.A., Gentry C., Alenmyr L., Killander D., Lewis S.E., Andersson A., Bucher B., Galzi J.-L., Sterner O., Bevan S., Högestätt E.D., Zygmunt P.M.
TRPA1 mediates spinal antinociception induced by acetaminophen and the cannabinoid delta9-tetrahydrocannabiorcol.
Nature Communications 2011 2, 551 - DOI

Daubeuf F., Gasparik V., Hachet-Haas M., Rohmer F., Gizzi P., Haiech J., Galzi J.-L., Hibert M., Bonnet D., Frossard N.
Activity of soluble CXCL12 neutraligands in vivo in a short model of asthma.
Inflammation research 2011 60, 112-113

Elhabazi K., Trigo J.-M., Mollereau C., Moulédous L., Zajac J.-M., Bihel F., Schmitt M., Bourguignon J.-J., Meziane H., Petit-demoulière B., Bockel F., Maldonado R., Simonin F.
Involvement of neuropeptide FF receptors in neuroadaptative responses to acute and chronic opiates treatments.
British J. Pharmacol. 2011 - DOI

Hachet-Haas M., Bonnet D., Daubeuf F., Hibert M., Haiech J., Frossard N., Galzi J.-L.
Les neutraligands à l’assaut des chimiokines.
BIOFUTUR 2011 319, 52-55

Jancso A., Selmeczi K., Gizzi P., Nagy N., Gajda T., Henry B.
The role of terminal amino group and histidine at the fourth position in the metal ion binding of oligopeptides revisited: Copper(II) and nickel(II) complexes of glycyl-glycyl-glycyl-histamine and its N-Boc protected derivative.
J. Inorg. Biochem. 2011 105, 92-101 - DOI

Lecat S., Ouédraogo M., Cherrier T., Noulet F., Rondé P., Glasser N., Galzi J.-L., Mely Y., Takeda K., Bucher B.
Contribution of a tyrosine-based motif to cellular trafficking of wild-type and truncated NPY Y(1) receptors.
Cell Signal. 2011 23, 228-38 - DOI

Mathis C., Bott J.-B., Candusso M.-P., Cassel, J.-C., Simonin F.
Impaired striatum-dependent behavior in GASP-1 knockout mice.
Genes, Brain and Behavior 2011 10, 299-308 - DOI

Renard M., Alkhalfioui F., Schmitt-Keichinger C., Ritzenthaler C., Montrichard F.
Identification and characterization of thioredoxin h isoforms differentially expressed in germinating seeds of the model legume Medicago truncatula.
Plant Physiol. 2011 155, 1113-26 - DOI

Top of page

 

- 2010

Abu-Helo A., Simonin F.
Identification and biological significance of G protein-coupled receptor associated sorting proteins (GASP).
Pharmacol. Ther. 2010 126, 244-50 - DOI

Benmaamar R., Wagner R., Pereira C.A.
Rabies prevention: Current trends in anti-rabies vaccines.
In: Rabies: Symptoms, Treatment and Prevention 2010 Editor: John G. Williamson, Nova Publishers -ISBN: 978-1-61122-332-3

Brillet K., Pereira C., Wagner R.
Expression of membrane proteins in Drosophila melanogaster S2 cells: production and analysis of a EGFP-fused G protein-coupled receptor as a model.
Methods Mol. Biol. 2010 601, 119-33 - DOI

Ferndahl C., Bonander N., Logez C., Wagner R., Gustafsson L., Larsson C., Hedfalk k., Darby R.A.J., Bill R.M.
Increasing cell biomass in Saccharomyces cerevisiae increases recombinant protein yield: the use of a respiratory strain as a microbial cell factory.
Microb. Cell. Fact. 2010 9, 47 - DOI" target="_blank">DOI

Galzi J-L., Hachet-Haas M., Bonnet D., Daubeuf F., Hibert M., Haiech J., Frossard N.
Neutralising endogeneous chemokines with small molecules. Principles and potential therapeutic applications.
Pharmacol. Ther. 2010 126, 39-55
DOI

Iturrioz X., Alvear-Perez R., De Mota N., Franchet C., Guillier F., Leroux V., Dabire H., Le Jouan M., Chabane H., Gerbier R., Bonnet D., Berdeaux A., Maigret B., Galzi J.L., Hibert M., Llorens-Cortes C.
Identification and pharmacological properties of E339-3D6, the first nonpeptidic apelin receptor agonist.
FASEB J. 2010 24, 1506-17 - DOI

Michalke K., Huyghe C., Lichière J., Gravière M.E., Siponen M., Sciara G., Lepaul I., Wagner R., Magg C., Rudolph R., Cambillau C., Desmyter A.
Mammalian G protein-coupled receptor expression in Escherichia coli: II. Refolding and biophysical characterization of mouse cannabinoid receptor 1 and human parathyroid hormone receptor 1.
Anal. Biochem. 2010 401, 74-80 - DOI

Quinton L., Girard E., Maiga E., Rekik M., Lluel P., Masuyer P., Larregola M., Marquer C., Ciolek J., Magnin T., Wagner R., Molgó J., Thai R., Fruchart-Gaillard C., Mourier G., Chamot-Rooke J., Ménez A., Palea S., Servent D., Gilles N.
Isolation and pharmacological characterisation of AdTx1, a natural peptide displaying specific insurmountable antagonism of the alpha1A-adrenoceptor.
Br. J. Pharmacol. 2010 159 316-325 - DOI

Top of page

 

- 2009

Alkhalfioui F, Magnin T, Wagner R.
From purified GPCRs to drug discovery: the promise of protein-based methodologies.
Curr. Opin. Pharmacol. 2009 9, 629-35 - DOI

Benmaamar R., Astray R., Wagner R., Pereira C.A.
High-level expression of rabies virus glycoprotein with the RNA-based Semliki Forest Virus expression vector.
J. Biotechnol. 2009 139, 283-90 - DOI

Bœuf J., Trigo J.M., Moreau P.-H., Lecourtier L., Vogel E., Cassel J.-C., Mathis C., Klosen P., Maldonado R., Simonin F.
Attenuated behavioural responses to acute and chronic cocaine in GASP-1 deficient mice.
European. J. Neurosci. 2009 30, 860-8 - DOI

Gizzi P., Pasc A., Dupuy N., Parant S., Henry B., Gérardin C.
Molecular tailored histidine-based complexing surfactants: from micelles to hydrogels.
Eur. J. Org. Chem. 2009 23, 3953-63

Greenwald J., Nader M., Célia, H., Gruffaz C., Geoffray V., Meyer J.-M., Schalk, I. J., Pattus F.
FpvA bound to non-cognate pyoverdines: molecular basis of siderophore recognition by an iron transporter.
Mol. Microbiol. 2009 72, 1246-59 - DOI

Ilien B., Glasser N., Clamme J.P. Didier P. Piemont E., Chinnappan R., Daval S.B., Galzi J.L., Mély, Y.
Pirenzepine promotes the dimerization of muscarinic M1 receptors through a three-step binding process.
J. Biol. Chem. 2009 284, 19533-43 - DOI

Ma L., MacTavish D., Simonin F., Bourguignon J.J., Watanabe T., Jhamandas J.H.
Prolactin-releasing peptide effects in the rat brain are mediated through the Neuropeptide FF receptor.
Eur J Neurosci. 2009 8, 1585-93 - DOI

Magnin T., Fiez-Vandal C., Potier N., Coquard A., Leray I., Steffan T., Logez C., Alkhalfioui F., Pattus F., Wagner R.
A novel, generic and effective method for the rapid purification of G protein-coupled receptors.
Protein Expr. Purif. 2009 64, 1-7 - DOI

Michalke K., Gravière M.-E., Huyghe C., Vincentelli R., Wagner R., Pattus F., Schroeder K., Oschmann J., Rudolph R., Cambillau C., Desmyter A.
Mammalian G-protein-coupled receptor expression in Escherichia coli: I. High-throughput large-scale production as inclusion bodies.
Anal. Biochem. 2009 386, 147-55 - DOI

Montrichard F., Alkhalfioui F., Yano H., Vensel W.H., Hurkman W.J., Buchanan B.B.
Thioredoxin targets in plants: the first 30 years.
J. Proteomics 2009 72, 452-74 - DOI

Valant C., Maillet E.L., Bourguignon J.J., Bucher B., Utard V., Galzi J-L., Hibert M.
Allosteric functional switch of neurokinin A-mediated signalling at the neurokinin NK2 receptor: structural exploration.
J. Med. Chem. 2009 52, 5999-6011 - DOI

Top of page

 

- 2008

Alkhalfioui F., Renard M., Frendo P., Keichinger C., Meyer Y., Gelhaye E., Hirasawa M., Knaff D.B., Ritzenthaler C., Montrichard F.
A novel type of thioredoxin dedicated to symbiosis in legumes.
Plant Physiol. 2008 148, 424-35 - DOI

Choul-Li S., Adams H., Pattus F., Célia H.
Visualization of interactions between siderophore transporters and the energizing protein TonB by native PAGE.
Electrophoresis 2008 29, 1333-8 - DOI

Greenwald J., Zeder-Lutz G., Hagege A., Célia H., Pattus F.
The metal dependence of pyoverdine interactions with its outer membrane receptor FpvA.
J. Bacteriol. 2008 190, 6548-58 - DOI

Hachet-Haas M., Balabanian K., Rohmer F., Pons F., Franchet C., Lecat S., Chow KYC, Dagher R., Gizzi P., Didier B., Lagane B., Kellenberger E., Bonnet D., Baleux F., Haiech J., Parmentier M., Frossard N., Arenzana-Seisdedos F., Hibert M,, Galzi J.-L.
Small neutralizing molecules to inhibit actions of the chemokine CXCL12.
J. Biol. Chem. 2008 283, 23189-99- DOI

Michalke K., Gravière M.E., Huyghe C., Vincentelli R., Wagner R., Pattus F., Schroeder K., Oschmann J., Rudolph R., Cambillau C., Desmyter A.
Mammalian G-protein-coupled receptor expression in Escherichia coli: I. High-throughput large-scale production as inclusion bodies.
Anal. Biochem. 2009 386, 147-55 - DOI

Nagy N.V., Gajda T., Henry B., Gizzi P., Paksi Z., Rockenbauer A.
EPR spectroscopy for studying equilibrium and structural properties of copper(II) - small bioligand complexes in aqua solutions.
Metal ions in biology and medicine, 2008 10, 505-511

Nedelkina S., Gokce I., Ridley H., Weckerle C., Magnin T., Vallette F., Pattus F., Lakey J.H., Bechinger B.
High-yield expression and purification of soluble forms of the anti-apoptotic Bcl-x(L) and Bcl-2 as TolAIII-fusion proteins.
Protein Expr. Purif. 2008 60, 214-20 - DOI

Ouédraogo, M., Lecat, S., Rochdi, M.D., Hachet-Haas, M., Matthes, H., Gicquiaux, H., Verrier, S., Gaire, M., Glasser, N., Mély, Y., Takeda, K., Bouvier, M., Galzi, J.L., Bucher, B.
Distinct motifs of neuropeptide Y receptors differentially regulate trafficking and desensitization.
Traffic 2008 9, 305-324 - DOI

Singh S., Gras A., Fiez-Vandal C., Ruprecht J., Rana R., Martinez M., Strange P.G., Wagner R., Byrne B.
Large-scale functional expression of WT and truncated human adenosine A2A receptor in Pichia pastoris bioreactor cultures.
Microb. Cell. Fact. 2008 7, 28 - DOI

Top of page

 

- 2007

Alkhalfioui F., Renard M., Montrichard F.
Unique properties of NADP-thioredoxin reductase C in legumes.
J. Exp. Bot. 2007 58, 969-78 - DOI

Alkhalfioui F., Renard M., Vensel W.H., Wong J., Tanaka C.K., Hurkman W.J., Buchanan B.B., Montrichard F.
Thioredoxin-linked proteins are reduced during germination of Medicago truncatula seeds.
Plant Physiol. 2007 144, 1559-79 - DOI

Brillet K., Journet L., Célia H., Paulus L., Stahl A., Pattus F., Cobessi D.
A beta-strand lock-exchange for signal transduction in TonB-dependent transducers on basis of a common structural motif.
Structure 2007 15, 1383-91 - DOI

Kellenberger E., Springael J.Y., Parmentier M., Hachet-Haas M., Galzi J.L., Rognan D.
Identification of nonpeptide CCR5 receptor agonists by structure-based virtual screening.
J. Med. Chem. 2007 50, 1294-303 - DOI

Jhamandas, J.H., Simonin F., Bourguignon J.J., Harris K.H.
Neuropeptide FF and neuropeptide VF inhibit GABAergic neurotransmission in parvocellular neurons of the rat hypothalamic paraventricular nucleus.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007 292, R1872-80 - DOI

Maillet E.L., Pellegrini N., Valant C., Bucher B., Hibert M., Bourguignon J.J., Galzi J.L.
A novel, conformation-specific allosteric inhibitor of the tachykinin NK2 receptor (NK2R) with functionally selective properties.
FASEB J. 2007 21, 2124-34 - DOI

Wirth C., Meyer-Klaucke W., Pattus F., Cobessi D.
From the periplasmic signaling domain to the extracellular face of an outer membrane signal transducer of Pseudomonas aeruginosa: crystal structure of the ferric pyoverdine outer membrane receptor.
J. Mol. Biol. 2007 368, 398-406 - DOI

Zoffmann S., Bertrand S., Do Q.T., Bertrand D., Rognan D., Hibert M., Galzi J.L.
Topological analysis of the complex formed between neurokinin A and the NK2 tachykinin receptor.
J. Neurochem. 2007 101, 506-16 - DOI

Top of page

 

- 2006

Adams, H., G. Zeder-Lutz, I. Schalk, F. Pattus, H. Célia
Interaction of TonB with the outer membrane receptor FpvA of Pseudomonas aeruginosa.
J. Bacteriol. 2006 188, 5752-61

Andre, N., N. Cherouati, C. Prual, T. Steffan, G. Zeder-Lutz, T. Magnin, F. Pattus, H. Michel, R. Wagner, C. Reinhart
Enhancing functional production of G protein-coupled receptors in Pichia pastoris to levels required for structural studies via a single expression screen.
Protein Sci. 2006 15, 1115-26

Bonnet, D., B. Ilien, J.L. Galzi, S. Riche, C. Antheaune, M. Hibert
A rapid and versatile method to label receptor ligands using "click" chemistry: Validation with the muscarinic M1 antagonist pirenzepine.
Bioconjug. Chem. 2006 17, 1618-23

Bourguignon, J.J., G. Simonnet, F. Simonin
RF9, a powerful and selective antagonist of the neuropeptide FF receptors, prevents the development of the tolerance to opioids.
Med. Sci (Paris) 2006 22, 579-80

Brillet, K., M.M. da Conceicao, F. Pattus, C.A. Pereira
Bioprocess parameters of cell growth and human mu opioid receptor expression in recombinant Drosophila S2 cell cultures in a bioreactor.
Bioprocess Biosyst. Eng. 2006 28, 291-3

Galzi J.-L., Maillet E., Lecat S., Hachet-Haas M., Haiech J., Hibert M., Ilien B.
Allosteric properties and regulation of G protein-coupled receptors».
In: «Ligand-design for GPCRs» 2006 Vol. 30 (Wiley ed.) pp 99-114

Haiech J., Galzi J.-L., Kilhoffer, Hibert M., Rognan D.
Why G protein-coupled receptors databases are needed».
In: «Ligand-design for GPCRs» 2006 Vol. 30 (Wiley ed.) pp 27-38

Hassaine, G., R. Wagner, J. Kempf, N. Cherouati, N. Hassaine, C. Prual, N. Andre, C. Reinhart, F. Pattus, K. Lundstrom
Semliki Forest virus vectors for overexpression of 101 G protein-coupled receptors in mammalian host cells.
Protein Expr. Purif. 2006 45, 343-51

Hachet-Haas, M., N. Converset, O. Marchal, H. Matthes, S. Gioria, J.L. Galzi, S. Lecat
FRET and colocalization analyzer: a method to validate measurements of sensitized emission FRET acquired by confocal microscopy and available as an ImageJ plug-in.
Microsc. Res. Tech. 2006 69, 941-56

Lundstrom, K., R. Wagner, C. Reinhart, A. Desmyter, N. Cherouati, T. Magnin, G. Zeder-Lutz, M. Courtot, C. Prual, N. Andre, G. Hassaine, H. Michel, C. Cambillau, F. Pattus
Structural genomics on membrane proteins: comparison of more than 100 GPCRs in 3 expression systems.
J. Struct. Funct. Genomics 2006 7, 77-91

Mdzinarashvili, T., M. Khvedelidze, A. Ivanova, G. Mrevlishvili, M. Kutateladze, N. Balarjishvili, H. Célia, F. Pattus
Biophysics of T5, IRA phages, Escherichia coli outer membrane protein FhuA and T5-FhuA interaction.
Eur. Biophys. J. 2006 35, 231-8

Simonin, F.
Neuropeptide FF receptors as therapeutic targets.
Drugs of the Future 2006 31, 603-609.

Simonin, F., M. Schmitt, J.P. Laulin, E. Laboureyras, J.H. Jhamandas, D. MacTavish, A. Matifas, C. Mollereau, P. Laurent, M. Parmentier, B.L. Kieffer, J.J. Bourguignon, G. Simonnet
RF9, a potent and selective neuropeptide FF receptor antagonist, prevents opioid-induced tolerance associated with hyperalgesia.
Proc. Natl Acad. Sci. USA 2006 103, 466-71.

Wirth, C., F. Hoegy, F. Pattus, D. Cobessi
Preliminary X-ray investigations of several crystal forms of the ferripyoverdine FpvA outer membrane receptor from Pseudomonas aeruginosa bound to ferripyoverdine.
Acta Crystallograph. F Struct. Biol. Cryst. Commun 2006 62, 460-3.

Zeder-Lutz, G., N. Cherouati, C. Reinhart, F. Pattus, R. Wagner
Dot-blot immunodetection as a versatile and high-throughput assay to evaluate recombinant GPCRs produced in the yeast Pichia pastoris.
Protein Expr. Purif. 2006 50, 118-27.

Top of page

 

- 2005

Baurand, A., A. Eckly, B. Hechler, G. Kauffenstein, J.L. Galzi, J.P. Cazenave, C. Leon, C. Gachet
Differential regulation and relocalization of the platelet P2Y receptors after activation: a way to avoid loss of hemostatic properties?
Mol. Pharmacol. 2005 67, 721-33

Cluet, D., C. Bertsch, C. Beyer, L. Gloeckler, M. Erhardt, J.P. Gut, J.L. Galzi, A.M. Aubertin
Detection of human immunodeficiency virus type 1 Nef and CD4 physical interaction in living human cells by using bioluminescence resonance energy transfer.
J. Virol. 2005 79, 8629-36

Gizzi P., Henry B., Rubini P., Giroux S., Wenger E.
A multi-approach study of the interaction of Cu(II) and Ni(II) ions with ala- nylglycylhistamine, a mimicking pseudopeptide of the serum albumine N- terminal residue.
J. Inorg. Biochem. 2005 99, 1182-1192

Haas M., Geldreich A., Bureau M., Dupuis L., Vetter G.Leh V., Kobayashi K., Hohn T., Ryabova L.,Yot P., Keller M.
The ORF VI product of Cauliflower mosaic virus is a nucleocytoplasmic protein : its N terminus mediates its nuclear export and formation of electron- dense viroplasms.
Plant Cell 2005 17, 1-17

Kovacs, K.M., I. Szakall, D. O’Brien, R. Wang, K.Y. Vinod, M. Saito, F. Simonin, B.L. Kieffer, C. Vadasz
Decreased oral self-administration of alcohol in kappa-opioid receptor knock-out mice.
Alcohol Clin. Exp. Res. 2005 29, 730-8

Top of page

 

- 2004

Cezanne, L., S. Lecat, B. Lagane, C. Millot, J.Y. Vollmer, H. Matthes, J.L. Galzi, A. Lopez
Dynamic confinement of NK2 receptors in the plasma membrane. Improved FRAP analysis and biological relevance.
J. Biol. Chem. 2004 279, 45057-67

De Mey, D., Galzi J.-L.
Cancéropôle et Strasbourg-Alsace-Lorraine-Génopole : Une synergie pour combattre le cancer.
Biofutur 2004 245, 37-40

Simonin, F., P. Karcher, J.J. Boeuf, A. Matifas, B.L. Kieffer
Identification of a novel family of G protein-coupled receptor associated sorting proteins.
J. Neurochem. 2004 89, 766-75

Tahtaoui, C., I. Parrot, P. Klotz, F. Guillier, J.L. Galzi, M. Hibert, B. Ilien
Fluorescent pirenzepine derivatives as potential bitopic ligands of the human M1 muscarinic receptor.
J. Med. Chem. 2004 47, 4300-15

Top of page

 

- 2003

Gaveriaux-Ruff, C., F. Simonin, D. Filliol, B.L. Kieffer
Enhanced humoral response in kappa-opioid receptor knockout mice.
J. Neuroimmunol. 2003 134, 72-81

Ilien, B., C. Franchet, P. Bernard, S. Morisset, C.O. Weill, J.J. Bourguignon, M. Hibert; J.L. Galzi
Fluorescence resonance energy transfer to probe human M1 muscarinic receptor structure and drug binding properties.
J. Neurochem. 2003 85, 768-78

Jamot, L., H.W. Matthes, F. Simonin, B.L. Kieffer, J.C. Roder
Differential involvement of the mu and kappa opioid receptors in spatial learning.
Genes Brain Behav. 2003 2, 80-92

Perret, B.G., R. Wagner, S. Lecat, K. Brillet, G. Rabut, B. Bucher, F. Pattus
Expression of EGFP-amino-tagged human mu opioid receptor in Drosophila Schneider 2 cells: a potential expression system for large-scale production of G-protein coupled receptors.
Protein Expr. Purif. 2003 31, 123-32

Top of page

 

- 2002

Gicquiaux H., Lecat S., Gaire M., Dieterlen A., Mély Y., Takeda K., Bucher B., Galzi J.-L.
Rapid internalization and recycling of the human neuropeptide Y Y(1) receptor.
J. Biol. Chem. 2002 277, 6645-55

Lecat S., Bucher B., Mély Y., Galzi J.-L.
Mutations in the extracellular amino-terminal domain of the NK2 neurokinin receptor abolish cAMP signaling but preserve intracellular calcium responses.
J. Biol. Chem. 2002 277, 42034-48

Zoffmann S., Chollet A., Galzi J.-L.
Identification of the extracellular loop 2 as the point of interaction between the N terminus of the chemokine MIP-1alpha and its CCR1 receptor.
Mol. Pharmacol. 2002 62, 729-36

Top of page

 

- 2001

Palanche T., Ilien B., Zoffmann S., Reck M.-P., Bucher B., Edelstein S.J., Galzi J.-L.
The neurokinin A receptor activates calcium and cAMP responses through distinct conformational states
J. Biol. Chem. 2001 276, 34853-61

Valenzuela-Fernández A., Palanche T., Amara A., Magerus A., Altmeyer R., Delaunay T., Virelizier J.L., Baleux F., Galzi J.L., Arenzana-Seisdedos F.
Optimal inhibition of X4 HIV isolates by the CXC chemokine stromal cell-derived factor 1 alpha requires interaction with cell surface heparan sulfate proteoglycans.
J. Biol. Chem. 2001 276, 26550-8

Zoffmann S., Turcatti G., Galzi J., Dahl M., Chollet A.
Synthesis and characterization of fluorescent and photoactivatable MIP-1alpha ligands and interactions with chemokine receptors CCR1 and CCR5.
J. Med. Chem. 2001 44, 215-22

Top of page

- Back to the team home page