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Accueil > Infos et Pages pratiques > Le monde de la recherche > Science dans tous les sens > Immortality improves cell reprogramming

Immortality improves cell reprogramming

12 août 2009



Knocking out genes with a role in cancer prevention helps produce stem cells.

Switching off the p53 pathway helped researchers to make stem-like cells.

Specialized adult cells made ’immortal’ through the blockade of an antitumour pathway can be turned into stem-like cells quickly and efficiently.

The findings — which should make it easier to generate patient-specific cells from any tissue type, including certain diseased cells that have proved difficult to transform — suggest that cellular reprogramming and cancer formation are inextricably linked.

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